111 - Preeclamsia
Autor(s): A. Curti, G. Simonazzi, N. Rizzo
Issue: RIMeL - IJLaM, Vol. 6, N. 2, 2010 (MAF Servizi srl ed.)
Page(s): 111-114
Hypertensive disorders complicate approximately 10- 20% of pregnancies and cover a spectrum of different clinical pictures with varying impact on the health of mother and fetus. Among these pre-eclampsia (PE) represents the most severe form, being alone responsible for 15-20% of cases of maternal mortality and a major cause of perinatal mortality and morbidity. The clinical significance of hypertensive disorders in pregnancy is also linked to the possibility of serious maternal complications represented by HELLP syndrome (characterized by hemolysis, elevated liver function and low platelet count), eclampsia and disseminated intravascular coagulation (DIC). Laboratory monitoring of indices (blood count, platelet count, liver function, renal function, uric acid, LDH, proteinuria, etc.), associated with the evaluation of the patient’s clinical condition, is the only tool available to the clinical diagnosis and subsequent management of various conditions, with particular reference to the timing of childbirth, the only real treatment of PE.